J. K. Henske, S. E. Wilken, K. V. Solomon, C. E. Smallwood, V. Shutthanandan, J. E. Evans, M. K. Theodorou, M. A. O’Malley, “Metabolic characterization of anaerobic fungi provides a path forward for consolidated bioprocessing of crude lignocellulose,” Submitted.
X. Peng, C. L. Swift, M. K. Theodorou, M. A. O’Malley, “Methods for genomic characterization & maintenance of anaerobic fungi,” Submitted.
C. H. Haitjema, S. P. Gilmore, J. K. Henske, K. V. Solomon, R. deGroot, A. Kuo, S. Mondo, A. Kuo, S. J. Mondo, A. A. Salamov, K. LaButti, Z. Zhao, J. Chiniquy, K. Barry, H. M. Brewer, S. O. Purvine, A. T. Wright, M. Hainaut, B. Boxma, T. van Alen, J. H. P. Hackstein, B. Henrissat, S. E. Baker, I. V. Grigoriev, M. A. O’Malley, “A parts list for fungal cellulosomes revealed by comparative genomics,”Nature Microbiology, (2017) In press.
S. J. Mondo, R. O. Dannebaum, R. Kuo, K. LaButti, S. Haridas, A. Kuo, A. Salamov, S. R. Ahrendt, A. Lipzen, W. Sullivan, W. Andreopolous, A. Clum, E. Lindquist, C. Daum, G. Ramamoorthy, A. Gryganskyi, D. Dulley, J. Magnuson, T. Y. James, M. A. O’Malley, J. E. Stajich, J. W. Spatafora, A. Visel, I. V. Grigoriev, “Widespread adenine N6-methylation of active genes in fungi", Nature Genetics, (2017) In press.
S. P. Gilmore, J. K. Henske, J. A. Sexton, K. V. Solomon, S. Seppala, J. I. Yoo, L. M. Huyett, A. Pressman, J. Z. Cogan, V. Kivenson, X. Peng, Y. Tan, D. L. Valentine, M. A. O'Malley, "Genomic analysis of Methanobacterium bryantii, Methanosarcina spelaei, Methanosphaera cuniculi, and Methanocorpusculum parvum reveals a shift towards energy conservation in the genomes of methanogenic archaea," In revision.
S. Seppala, K. V. Solomon, S. P. Gilmore, J. K. Henske, M. A. O’Malley, “Mapping the membrane proteome of anaerobic fungi identifies a wealth of carbohydrate binding proteins and transporters”, Microbial Cell Factories, 15:212 (2016). [MCF]
J. Niu, D. J. Lunn, A. Pusuluri, J. I. Yoo, M. A. O'Malley, S. Mitragotri, H. T. Soh, C. J. Hawker," Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization," Nature Chemistry, (2016) In press. [Nature]
X. Peng, S. P. Gilmore, M. A. O’Malley, “Microbial communities for bioprocessing: lessons learned from nature,” Current Opinion in Chemical Engineering, 14: 103-109 (2016). [CurrOpChe]
N. S. Schonenbach, M. D. Rieth, S. Han, M. A. O’Malley, “Adenosine A2a receptors form distinct oligomers in protein detergent complexes,” FEBS Letters, 590: 3295-3306 (2016). [FEBS]
J. L. Guerrero, P. S. Daugherty, M. A. O'Malley, "Emerging technologies for protease engineering: new tools to clear out disease," Biotechnology & Bioengineering, 114(1): 33-38 (2017). [B&B]
G. J. Li et. al (+134 additional authors, including K. V. Solomon, J. K. Henske, C. H. Haitjema, S. P. Gilmore, M. K. Theodorou, M. A. O'Malley), "Fungal diversity notes 253-366: taxonomic and phylogenetic contributions to fungal taxa," Fungal Diversity, 78(1): 1-237 (2016). [FD]
K. V. Solomon, E. Ovadia, F. Yu, W. Mizunashi, M. A. O'Malley, "Mitochondrial-targeting increases specific activity of a heterologous valine assimilation pathway in Saccharomyces cerevisiae," Metabolic Engineering Communications, 3: 68-75 (2016). [MEX]
K. V. Solomon, C. H. Haitjema, J. K. Henske, S. P. Gilmore, D. Borges-Rivera, A. Lipzen, H. M. Brewer, S. O. Purvine, A. T. Wright, M. K. Theodorou, I. Grigoriev, A. Regev, D. A. Thompson, M. A. O’Malley, “Early-branching gut fungi possess a large, comprehensive array of biomass degrading enzymes,” Science, 351: 1192-1195 (2016). [Science]
J. L. Guerrero, M. A. O'Malley, P. S. Daugherty, "Intracellular FRET-based screen for redesigning the specificity of secreted proteases," ACS Chemical Biology, 11(4): 961-970 (2016). [ACS]
J. K. Henske, K. V. Solomon, M. K. Theodorou, M. A. O'Malley, "Robust and effective methodologies for cryopreservation and DNA extraction for anaerobic gut fungi, Anaerobe, 38:39-46 (2016). [Anaerobe]
S. P. Gilmore, J. K. Henske, M. A. O'Malley, "Driving biomass breakdown through engineered cellulosomes," Bioengineered, 6:4, 204-208 (2015). [BioE]
M. A. O’Malley, Y. Zhong, J. K. Henske, M. K. Theodorou, C. A. Kaiser, “A novel monocentric anaerobic fungus displays substrate-specific repression of cellulolytic behavior,” In preparation.
N. S. Schonenbach, S. Hussain, M. A. O’Malley, “Structure and function of G-protein coupled receptor oligomers: implications for drug discovery,” WIRES Nanomedicine and Nanobiotechnology, 7: 408-427 (2015). [WIRES]
K. V. Solomon, C. H. Haitjema, D. A. Thompson, M. A. O'Malley, "Extracting data from the muck: deriving biological insight from complex microbial communities and non-model organisms with next generation sequencing," Current Opinion in Biotechnology, 28: 103-110 (2014). [CoBIOT]
C. H. Haitjema, K. V. Solomon, J. K. Henske, M. K. Theodorou, M. A. O'Malley, "Anaerobic gut fungi: advances in isolation, culture, and cellulolytic enzyme discovery for biofuel production," Biotechnology & Bioengineering, 111(8): 1471-1482 (2014). [B&B]
M. A. O’Malley, M. K. Theodorou, C. A. Kaiser, “Evaluating expression and catalytic activity of anaerobic fungal fibrolytic enzymes native to Piromyces sp E2 in Saccharomyces cerevisiae,” Environmental Progress and Sustainable Energy, 31(1): 37-46 (2012). [EPSE] (Most Accessed Article)
M. A. O’Malley. “Neuromethods, Vol. 60: Methods for the Discovery and Characterization of G Protein-Coupled Receptors, edited by Craig W. Stevens”, ChemBioChem, 13(6): 905-906 (2012) . (Book Review) [ChemBioChem]
M. A. O’Malley, M. E. Helgeson, N. J. Wagner, A. S. Robinson, “Toward rational design of protein detergent complexes: determinants of mixed micelles that are critical for the in vitro stabilization of a G-protein coupled receptor,” Biophysical Journal, 101(8): 1938-1948 (2011). [pubmed]
M. A. O’Malley, M. E. Helgeson, N. J. Wagner, A. S. Robinson, “The morphology and composition of cholesterol-rich micellar nanostructures determine transmembrane protein (GPCR) activity,” Biophysical Journal, 100(2):L11-L13 (2011). (Featured Article, Most Accessed Article) [pubmed]
M. A. O’Malley, A. N. Naranjo, T. Lazarova, A. S. Robinson, “Analysis of adenosine A2a receptor stability: effects of ligands and disulfide bonds,” Biochemistry, 49: 9181-9189 (2010). [pubmed]
M. A. O’Malley, J. D. Mancini, C. L. Young, E. C. McCusker, D. Raden, A. S. Robinson, “Progress towards heterologous expression of active G-protein coupled receptors in Saccharomyces cerevisiae: linking cellular stress responses with translocation and trafficking,” Protein Science, 18(11):2356-2370 (2009). [pubmed]
M. A. O’Malley, T. Lazarova, Z. T. Britton, A. S. Robinson, “High-level expression in Saccharomyces cerevisiae enables isolation and spectroscopic characterization of functional human adenosine A2a receptor,” Journal of Structural Biology, 159:166-178 (2007). [pubmed]
E. C. McCusker, S. E. Bane, M. A. O’Malley, A. S. Robinson, “Heterologous GPCR expression: a bottleneck to obtaining crystal structures,” Biotechnology Progress, 23(3):540-547 (2007). [pubmed]
A. Wedekind, M. A. O’Malley, R. T. Niebauer, A. S. Robinson, “Optimization of the human adenosine A2a receptor yields in Saccharomyces cerevisiae,” Biotechnology Progress, 22(5):1249-1255 (2006). [pubmed]